Dynamics of plasma biomarkers in Down syndrome: the relative levels of Aβ42 decrease with age, whereas NT1 tau and NfL increase

BACKGROUND: Down syndrome (DS) is the most common genetic cause of Alzheimer’s disease (AD), but diagnosis of AD in DS is challenging due to the intellectual disability which accompanies DS. When disease-modifying agents for AD are approved, reliable biomarkers will be required to identify when and...

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Detalles Bibliográficos
Autores principales: Mengel, David, Liu, Wen, Glynn, Robert J., Selkoe, Dennis J., Strydom, Andre, Lai, Florence, Rosas, H. Diana, Torres, Amy, Patsiogiannis, Vasiliki, Skotko, Brian, Walsh, Dominic M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081580/
https://www.ncbi.nlm.nih.gov/pubmed/32192521
http://dx.doi.org/10.1186/s13195-020-00593-7

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