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Comparison of toxic responses to acetaminophen challenge in ICR mice originating from different sources

Acetaminophen (APAP) is the most common antipyretic analgesic worldwide. However, APAP overdose causes severe liver injury, especially centrilobular necrosis, in humans and experimental animals. At therapeutic dosage, APAP is mainly metabolized by sulfation and glucuronidation, and partly by cytochr...

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Detalles Bibliográficos
Autores principales:	Jeong, Tae Bin, Kim, Joung-Hee, Kim, Sou Hyun, Lee, Seunghyun, Son, Seung Won, Lim, Yong, Cho, Joon-Yong, Hwang, Dae Youn, Kim, Kil Soo, Kwak, Jae-Hwan, Jung, Young-Suk
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081583/ https://www.ncbi.nlm.nih.gov/pubmed/32257904 http://dx.doi.org/10.1186/s42826-019-0017-x

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