Palladium-Catalyzed Synthesis and Anticancer Activity of Paclitaxel–Dehydroepiandrosterone Hybrids

[Image: see text] According to the activity–structure relationship of the C-13 side chain in paclitaxel or docetaxel, eighteen novel paclitaxel–dehydroepiandrosterone (DHEA) hybrids were designed and synthesized by Pd(II)-catalyzed Suzuki–Miyaura cross-coupling of 17-trifluoromethanesulfonic enolate...

Descripción completa

Detalles Bibliográficos
Autores principales: Lou, Sheng-Jie, Li, Xiao-Huan, Zhou, Xian-Li, Fang, Dong-Mei, Gao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081646/
https://www.ncbi.nlm.nih.gov/pubmed/32201853
http://dx.doi.org/10.1021/acsomega.0c00558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081646/
https://www.ncbi.nlm.nih.gov/pubmed/32201853
http://dx.doi.org/10.1021/acsomega.0c00558

Ejemplares similares