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Palladium-Catalyzed Synthesis and Anticancer Activity of Paclitaxel–Dehydroepiandrosterone Hybrids

[Image: see text] According to the activity–structure relationship of the C-13 side chain in paclitaxel or docetaxel, eighteen novel paclitaxel–dehydroepiandrosterone (DHEA) hybrids were designed and synthesized by Pd(II)-catalyzed Suzuki–Miyaura cross-coupling of 17-trifluoromethanesulfonic enolate...

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Detalles Bibliográficos
Autores principales:	Lou, Sheng-Jie, Li, Xiao-Huan, Zhou, Xian-Li, Fang, Dong-Mei, Gao, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081646/ https://www.ncbi.nlm.nih.gov/pubmed/32201853 http://dx.doi.org/10.1021/acsomega.0c00558

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