Cargando…
Palladium-Catalyzed Synthesis and Anticancer Activity of Paclitaxel–Dehydroepiandrosterone Hybrids
[Image: see text] According to the activity–structure relationship of the C-13 side chain in paclitaxel or docetaxel, eighteen novel paclitaxel–dehydroepiandrosterone (DHEA) hybrids were designed and synthesized by Pd(II)-catalyzed Suzuki–Miyaura cross-coupling of 17-trifluoromethanesulfonic enolate...
Autores principales: | Lou, Sheng-Jie, Li, Xiao-Huan, Zhou, Xian-Li, Fang, Dong-Mei, Gao, Feng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2020
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081646/ https://www.ncbi.nlm.nih.gov/pubmed/32201853 http://dx.doi.org/10.1021/acsomega.0c00558 |
Ejemplares similares
-
Molecular-docking-guided design, palladium-catalyzed synthesis and anticancer activity of paclitaxel-benzoxazoles hybrids
por: Jiang, Ting, et al.
Publicado: (2022) -
Palladium-Catalyzed Synthesis of Cyclopropylthiophenes and Their Derivatization
por: Paškevičius, Tomas, et al.
Publicado: (2023) -
Cyclic Alkenylsulfonyl Fluorides: Palladium‐Catalyzed Synthesis and Functionalization of Compact Multifunctional Reagents
por: Lou, Terry Shing‐Bong, et al.
Publicado: (2019) -
Ligand-dependent, palladium-catalyzed stereodivergent synthesis of chiral tetrahydroquinolines
por: Wang, Yue, et al.
Publicado: (2022) -
Palladium-catalyzed oxidative cross-coupling for the synthesis of α-amino ketones
por: Wei, Xiao-Hong, et al.
Publicado: (2019)