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Characterization and applications of chimeric mice with humanized livers for preclinical drug development
We have succeeded in stable mass production of chimeric PXB-mice, whose liver is repopulated by human hepatocytes at a ratio of more than 70%, and we are providing these mice to academia and pharmaceutical companies to support the development of new drugs or studies of liver function. Furthermore, w...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081693/ https://www.ncbi.nlm.nih.gov/pubmed/32206609 http://dx.doi.org/10.1186/s42826-019-0032-y |