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Cathepsin K regulates localization and secretion of Tartrate-Resistant Acid Phosphatase (TRAP) in TRAP-overexpressing MDA-MB-231 breast cancer cells

BACKGROUND: Tartrate–resistant acid phosphatase (TRAP/ ACP5) belongs to the binuclear metallophosphatase family and is present in two isoforms. The primary translation product is an uncleaved TRAP 5a isoform with low phosphatase activity. TRAP 5a can be post-translationally processed to a cleaved TR...

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Detalles Bibliográficos
Autores principales:	Reithmeier, Anja, Norgård, Maria, Ek-Rylander, Barbro, Näreoja, Tuomas, Andersson, Göran
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081696/ https://www.ncbi.nlm.nih.gov/pubmed/32188406 http://dx.doi.org/10.1186/s12860-020-00253-6

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