Novel Anti-Interleukin-1β Therapy Preserves Retinal Integrity: A Longitudinal Investigation Using OCT Imaging and Automated Retinal Segmentation in Small Rodents

Retinopathy of prematurity (ROP) is the leading cause of blindness in neonates. Inflammation, in particular interleukin-1β (IL-1β), is increased in early stages of the disorder, and contributes to inner and outer retinal vasoobliteration in the oxygen-induced retinopathy (OIR) model of ROP. A small...

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Detalles Bibliográficos
Autores principales: Sayah, Diane N., Zhou, Tianwei E., Omri, Samy, Mazzaferri, Javier, Quiniou, Christiane, Wirth, Maëlle, Côté, France, Dabouz, Rabah, Desjarlais, Michel, Costantino, Santiago, Chemtob, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081735/
https://www.ncbi.nlm.nih.gov/pubmed/32226385
http://dx.doi.org/10.3389/fphar.2020.00296

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