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Preparation, characterization, and in vitro/vivo evaluation of polymer-assisting formulation of atorvastatin calcium based on solid dispersion technique

Due to low solubility and bioavailability, atorvastatin calcium is confronted with challenge in conceiving appropriate formulation. Solid dispersion of atorvastatin calcium was prepared through the solvent evaporation method, with Poloxamer 188 as hydrophilic carriers. This formulation was then char...

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Detalles Bibliográficos
Autores principales:	Dong, Wenxiang, Su, Xitong, Xu, Meng, Hu, Mingming, Sun, Yinghua, Zhang, Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Shenyang Pharmaceutical University 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081932/ https://www.ncbi.nlm.nih.gov/pubmed/32211078 http://dx.doi.org/10.1016/j.ajps.2018.08.010

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