Surfactant-enhanced DNA accessibility to nuclease accelerates phenotypic β-lactam antibiotic susceptibility testing of Neisseria gonorrhoeae

Rapid antibiotic susceptibility testing (AST) for Neisseria gonorrhoeae (Ng) is critically needed to counter widespread antibiotic resistance. Detection of nucleic acids in genotypic AST can be rapid, but it has not been successful for β-lactams (the largest antibiotic class used to treat Ng). Rapid...

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Detalles Bibliográficos
Autores principales: Savela, Emily S., Schoepp, Nathan G., Cooper, Matthew M., Rolando, Justin C., Klausner, Jeffrey D., Soge, Olusegun O., Ismagilov, Rustem F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Methods and Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081974/
https://www.ncbi.nlm.nih.gov/pubmed/32191696
http://dx.doi.org/10.1371/journal.pbio.3000651

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