Cargando…

Reproducibility warning: The curious case of polyethylene glycol 6000 and spheroid cell culture

Reproducibility of results is essential for a well-designed and conducted experiment. Several reasons may originate failure in reproducing data, such as selective reporting, low statistical power, or poor analysis. In this study, we used PEG6000 samples from different distributors and tested their c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Serrati, Simona, Martinelli, Chiara, Palazzo, Antonio, Iacobazzi, Rosa Maria, Perrone, Mara, Ong, Quy K., Luo, Zhi, Bekdemir, Ahmet, Pinto, Giulia, Cavalleri, Ornella, Cutrignelli, Annalisa, Laquintana, Valentino, Denora, Nunzio, Stellacci, Francesco, Krol, Silke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082040/ https://www.ncbi.nlm.nih.gov/pubmed/32191706 http://dx.doi.org/10.1371/journal.pone.0224002

Ejemplares similares

TSPO Ligand-Methotrexate Prodrug Conjugates: Design, Synthesis, and Biological Evaluation
por: Laquintana, Valentino, et al.
Publicado: (2016)

Delivery of Proapoptotic Agents in Glioma Cell Lines by TSPO Ligand–Dextran Nanogels
por: Lopalco, Antonio, et al.
Publicado: (2018)

Transferrin Functionalized Liposomes Loading Dopamine HCl: Development and Permeability Studies across an In Vitro Model of Human Blood–Brain Barrier
por: Lopalco, Antonio, et al.
Publicado: (2018)

Hydroxy-Propil-β-Cyclodextrin Inclusion Complexes of two Biphenylnicotinamide Derivatives: Formulation and Anti-Proliferative Activity Evaluation in Pancreatic Cancer Cell Models
por: Iacobazzi, Rosa Maria, et al.
Publicado: (2020)

Stability data of extemporaneous suspensions of hydroxychloroquine sulphate in oral liquid bases after tablet manipulation
por: Perrone, Mara, et al.
Publicado: (2020)

Editorial: What does it take to cure the brain? Studies toward genes, proteins, processes, and rehabilitation
por: Shu, Xinhua, et al.
Publicado: (2023)

Effectiveness of a Controlled 5-FU Delivery Based on FZD10 Antibody-Conjugated Liposomes in Colorectal Cancer In vitro Models
por: Scavo, Maria Principia, et al.
Publicado: (2020)

Multi-sulfonated ligands on gold nanoparticles as virucidal antiviral for Dengue virus
por: Zacheo, Antonella, et al.
Publicado: (2020)

Microfluidic-Assisted Preparation of Targeted pH-Responsive Polymeric Micelles Improves Gemcitabine Effectiveness in PDAC: In Vitro Insights
por: Iacobazzi, Rosa Maria, et al.
Publicado: (2021)

A Novel PET Imaging Probe for the Detection and Monitoring of Translocator Protein 18 kDa Expression in Pathological Disorders
por: Perrone, Mara, et al.
Publicado: (2016)

Dasatinib/HP-β-CD Inclusion Complex Based Aqueous Formulation as a Promising Tool for the Treatment of Paediatric Neuromuscular Disorders
por: Cutrignelli, Annalisa, et al.
Publicado: (2019)

Direct cyclodextrin-based powder extrusion 3D printing for one-step production of the BCS class II model drug niclosamide
por: Pistone, Monica, et al.
Publicado: (2022)

Polyethylene Glycol(6000)/carbon Nanodots as Fluorescent Bioimaging Agents
por: Fu, Chun-Chieh, et al.
Publicado: (2020)

Imaging modification of colon carcinoma cells exposed to lipid based nanovectors for drug delivery: a scanning electron microscopy investigation
por: Depalo, Nicoletta, et al.
Publicado: (2019)

Fabrication of photoactive heterostructures based on quantum dots decorated with Au nanoparticles
por: Fanizza, Elisabetta, et al.
Publicado: (2016)

Efficaciousness of Low Affinity Compared to High Affinity TSPO Ligands in the Inhibition of Hypoxic Mitochondrial Cellular Damage Induced by Cobalt Chloride in Human Lung H1299 Cells
por: Zeineh, Nidal, et al.
Publicado: (2020)

The Neuro-Protective Effects of the TSPO Ligands CB86 and CB204 on 6-OHDA-Induced PC12 Cell Death as an In Vitro Model for Parkinson’s Disease
por: Monga, Sheelu, et al.
Publicado: (2021)

Synthesis and Evaluation of Tricarbonyl (99m)Tc-Labeled 2-(4-Chloro)phenyl-imidazo[1,2-a]pyridine Analogs as Novel SPECT Imaging Radiotracer for TSPO-Rich Cancer
por: Choi, Ji Young, et al.
Publicado: (2016)

FM19G11-Loaded Gold Nanoparticles Enhance the Proliferation and Self-Renewal of Ependymal Stem Progenitor Cells Derived from ALS Mice
por: Marcuzzo, Stefania, et al.
Publicado: (2019)

The hydroxypropyl‐β‐cyclodextrin‐minoxidil inclusion complex improves the cardiovascular and proliferative adverse effects of minoxidil in male rats: Implications in the treatment of alopecia
por: Maqoud, Fatima, et al.
Publicado: (2020)

Green Fluorescent Terbium (III) Complex Doped Silica Nanoparticles for TSPO Targeting
por: Fanizza, Elisabetta, et al.
Publicado: (2019)

Transcriptomic responses of Saccharum spontaneum roots in response to polyethylene glycol – 6000 stimulated drought stress
por: Wu, Kai-Chao, et al.
Publicado: (2022)

Polyphenols Epigallocatechin Gallate and Resveratrol, and Polyphenol-Functionalized Nanoparticles Prevent Enterovirus Infection through Clustering and Stabilization of the Viruses
por: Reshamwala, Dhanik, et al.
Publicado: (2021)

A centrifugation-based physicochemical characterization method for the interaction between proteins and nanoparticles
por: Bekdemir, Ahmet, et al.
Publicado: (2016)

The protective effect of the TSPO ligands 2,4-Di-Cl-MGV-1, CB86, and CB204 against LPS-induced M1 pro-inflammatory activation of microglia
por: Monga, Sheelu, et al.
Publicado: (2020)

Exploring the Microfluidic Production of Biomimetic Hybrid Nanoparticles and Their Pharmaceutical Applications
por: Fondaj, Dafina, et al.
Publicado: (2023)

Effects of Drought Stress Induced by Hypertonic Polyethylene Glycol (PEG-6000) on Passiflora edulis Sims Physiological Properties
por: Qi, Ying, et al.
Publicado: (2023)

Synthesis, Characterization, and Cytotoxicity of the First Oxaliplatin Pt(IV) Derivative Having a TSPO Ligand in the Axial Position
por: Savino, Salvatore, et al.
Publicado: (2016)

A temperature controller in the 6000 series
por: Cox, C E, et al.
Publicado: (1981)

Batch processing with 6000-series scope
por: Lipps, H
Publicado: (1971)

Bcr-Abl Tyrosine Kinase Inhibitors in the Treatment of Pediatric CML
por: Carofiglio, Francesca, et al.
Publicado: (2020)

Genetics of Ribosomal Proteins: “Curiouser and Curiouser”
por: Terzian, Tamara, et al.
Publicado: (2013)

A Harwell 6000 series microprocessing system
por: Phillips, G I
Publicado: (1979)

6000 a current leads for the BEBC magnet
por: CERN. Geneva. Super Proton Synchrotron Division (SPS)
Publicado: (1974)

Cytotoxicity Study on Luminescent Nanocrystals Containing Phospholipid Micelles in Primary Cultures of Rat Astrocytes
por: Latronico, Tiziana, et al.
Publicado: (2016)

FZD10 Carried by Exosomes Sustains Cancer Cell Proliferation
por: Scavo, Maria Principia, et al.
Publicado: (2019)

Radiosynthesis and characterization of [(18)F]BS224: a next-generation TSPO PET ligand insensitive to the rs6971 polymorphism
por: Lee, Sang Hee, et al.
Publicado: (2021)

β-Dystroglycan Restoration and Pathology Progression in the Dystrophic mdx Mouse: Outcome and Implication of a Clinically Oriented Study with a Novel Oral Dasatinib Formulation
por: Mantuano, Paola, et al.
Publicado: (2021)

Comparing the Positive Impacts and Stress Induction by Polyethylene Glycol (PEG 6000) Variable Levels on Canola (Brassica napus L.) Growth, Yield, and Oil Contents
por: Elahi, Nosheen Noor, et al.
Publicado: (2023)

Frizzled-10 Extracellular Vesicles Plasma Concentration Is Associated with Tumoral Progression in Patients with Colorectal and Gastric Cancer
por: Scavo, Maria Principia, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_lrh7hc6oeh4ddbiggkphns09kv