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Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein

Lasting protection has long been a goal for malaria vaccines. The major surface antigen on Plasmodium falciparum sporozoites, the circumsporozoite protein (PfCSP), has been an attractive target for vaccine development and most protective antibodies studied to date interact with the central NANP repe...

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Detalles Bibliográficos
Autores principales:	Oyen, David, Torres, Jonathan L., Aoto, Phillip C., Flores-Garcia, Yevel, Binter, Špela, Pholcharee, Tossapol, Carroll, Sean, Reponen, Sini, Wash, Rachael, Liang, Qi, Lemiale, Franck, Locke, Emily, Bradley, Allan, King, C. Richter, Emerling, Daniel, Kellam, Paul, Zavala, Fidel, Ward, Andrew B., Wilson, Ian A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082059/ https://www.ncbi.nlm.nih.gov/pubmed/32150583 http://dx.doi.org/10.1371/journal.ppat.1008373

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