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Parallel Tempering with Lasso for model reduction in systems biology
Systems Biology models reveal relationships between signaling inputs and observable molecular or cellular behaviors. The complexity of these models, however, often obscures key elements that regulate emergent properties. We use a Bayesian model reduction approach that combines Parallel Tempering wit...
Autores principales: | Gupta, Sanjana, Lee, Robin E. C., Faeder, James R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082068/ https://www.ncbi.nlm.nih.gov/pubmed/32150537 http://dx.doi.org/10.1371/journal.pcbi.1007669 |
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