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Family-wide Structural and Biophysical Analysis of Binding Interactions among Non-clustered δ-Protocadherins

Non-clustered δ1- and δ2-protocadherins, close relatives of clustered protocadherins, function in cell adhesion and motility and play essential roles in neural patterning. To understand the molecular interactions underlying these functions, we used solution biophysics to characterize binding of δ1-...

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Detalles Bibliográficos
Autores principales: Harrison, Oliver J., Brasch, Julia, Katsamba, Phinikoula S., Ahlsen, Goran, Noble, Alex J., Dan, Hanbin, Sampogna, Rosemary V., Potter, Clinton S., Carragher, Bridget, Honig, Barry, Shapiro, Lawrence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082078/
https://www.ncbi.nlm.nih.gov/pubmed/32101743
http://dx.doi.org/10.1016/j.celrep.2020.02.003