Early prediction of resistance to tyrosine kinase inhibitors by plasma monitoring of EGFR mutations in NSCLC: a new algorithm for patient selection and personalized treatment

In Non-Small-Cell Lung Cancer (NSCLC) patients treated with Tyrosine Kinase-Inhibitors (TKIs) therapy, the emergence of acquired resistance can be investigated by plasma monitoring of circulating tumor DNA (ctDNA). A series of 116 patients with EGFR-positive lung adenocarcinomas were treated with fi...

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Detalles Bibliográficos
Autores principales: Buttitta, Fiamma, Felicioni, Lara, Lorito, Alessia Di, Cortellini, Alessio, Irtelli, Luciana, Brocco, Davide, Marino, Pietro Di, Traisci, Donatella, D’Ostilio, Nicola, Paolo, Alessandra Di, Malorgio, Francesco, Assalone, Pasquale, Felice, Sonia Di, Fabbri, Francesca, Cianci, Giovanni, Tursi, Michele De, Marchetti, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082112/
https://www.ncbi.nlm.nih.gov/pubmed/32215186
http://dx.doi.org/10.18632/oncotarget.27517

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