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Repression of viral gene expression and replication by the unfolded protein response effector XBP1u

The unfolded protein response (UPR) is a cellular homeostatic circuit regulating protein synthesis and processing in the ER by three ER-to-nucleus signaling pathways. One pathway is triggered by the inositol-requiring enzyme 1 (IRE1), which splices the X-box binding protein 1 (Xbp1) mRNA, thereby en...

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Detalles Bibliográficos
Autores principales:	Hinte, Florian, van Anken, Eelco, Tirosh, Boaz, Brune, Wolfram
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082126/ https://www.ncbi.nlm.nih.gov/pubmed/32065579 http://dx.doi.org/10.7554/eLife.51804

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