In Support of Simian Polyomavirus 40 VP4 as a Later Expressed Viroporin

Simian virus 40 VP4 was discovered in 2007 as a later expressed viral protein initiated from a downstream Met on the VP2/VP3 transcript. VP4’s role as a viroporin involved in viral release was supported in a series of additional articles that characterized the ability of VP4 to associate with and pe...

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Detalles Bibliográficos
Autores principales: Daniels, Robert, Hebert, Daniel N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082142/
https://www.ncbi.nlm.nih.gov/pubmed/32188752
http://dx.doi.org/10.1128/mSphere.00187-20
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author Daniels, Robert
Hebert, Daniel N.
author_facet Daniels, Robert
Hebert, Daniel N.
author_sort Daniels, Robert
collection PubMed
description Simian virus 40 VP4 was discovered in 2007 as a later expressed viral protein initiated from a downstream Met on the VP2/VP3 transcript. VP4’s role as a viroporin involved in viral release was supported in a series of additional articles that characterized the ability of VP4 to associate with and permeabilize biological membranes. This commentary is our response to the perspective from Henriksen and Rinaldo (mSphere 5:e00019-20, 2020, https://doi.org/10.1128/mSphere.00019-20) that challenges the existence of SV40 VP4.
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spelling pubmed-70821422020-04-02 In Support of Simian Polyomavirus 40 VP4 as a Later Expressed Viroporin Daniels, Robert Hebert, Daniel N. mSphere Commentary Simian virus 40 VP4 was discovered in 2007 as a later expressed viral protein initiated from a downstream Met on the VP2/VP3 transcript. VP4’s role as a viroporin involved in viral release was supported in a series of additional articles that characterized the ability of VP4 to associate with and permeabilize biological membranes. This commentary is our response to the perspective from Henriksen and Rinaldo (mSphere 5:e00019-20, 2020, https://doi.org/10.1128/mSphere.00019-20) that challenges the existence of SV40 VP4. American Society for Microbiology 2020-03-18 /pmc/articles/PMC7082142/ /pubmed/32188752 http://dx.doi.org/10.1128/mSphere.00187-20 Text en Copyright © 2020 Daniels and Hebert. https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Commentary
Daniels, Robert
Hebert, Daniel N.
In Support of Simian Polyomavirus 40 VP4 as a Later Expressed Viroporin
title In Support of Simian Polyomavirus 40 VP4 as a Later Expressed Viroporin
title_full In Support of Simian Polyomavirus 40 VP4 as a Later Expressed Viroporin
title_fullStr In Support of Simian Polyomavirus 40 VP4 as a Later Expressed Viroporin
title_full_unstemmed In Support of Simian Polyomavirus 40 VP4 as a Later Expressed Viroporin
title_short In Support of Simian Polyomavirus 40 VP4 as a Later Expressed Viroporin
title_sort in support of simian polyomavirus 40 vp4 as a later expressed viroporin
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082142/
https://www.ncbi.nlm.nih.gov/pubmed/32188752
http://dx.doi.org/10.1128/mSphere.00187-20
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