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Autism spectrum disorder: definition, epidemiology, causes, and clinical evaluation

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social communication and the presence of restricted interests and repetitive behaviors. There have been recent concerns about increased prevalence, and this article seeks to elaborate on factors that may inf...

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Detalles Bibliográficos
Autores principales: Hodges, Holly, Fealko, Casey, Soares, Neelkamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082249/
https://www.ncbi.nlm.nih.gov/pubmed/32206584
http://dx.doi.org/10.21037/tp.2019.09.09
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author Hodges, Holly
Fealko, Casey
Soares, Neelkamal
author_facet Hodges, Holly
Fealko, Casey
Soares, Neelkamal
author_sort Hodges, Holly
collection PubMed
description Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social communication and the presence of restricted interests and repetitive behaviors. There have been recent concerns about increased prevalence, and this article seeks to elaborate on factors that may influence prevalence rates, including recent changes to the diagnostic criteria. The authors review evidence that ASD is a neurobiological disorder influenced by both genetic and environmental factors affecting the developing brain, and enumerate factors that correlate with ASD risk. Finally, the article describes how clinical evaluation begins with developmental screening, followed by referral for a definitive diagnosis, and provides guidance on screening for comorbid conditions.
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spelling pubmed-70822492020-03-23 Autism spectrum disorder: definition, epidemiology, causes, and clinical evaluation Hodges, Holly Fealko, Casey Soares, Neelkamal Transl Pediatr Review Article Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social communication and the presence of restricted interests and repetitive behaviors. There have been recent concerns about increased prevalence, and this article seeks to elaborate on factors that may influence prevalence rates, including recent changes to the diagnostic criteria. The authors review evidence that ASD is a neurobiological disorder influenced by both genetic and environmental factors affecting the developing brain, and enumerate factors that correlate with ASD risk. Finally, the article describes how clinical evaluation begins with developmental screening, followed by referral for a definitive diagnosis, and provides guidance on screening for comorbid conditions. AME Publishing Company 2020-02 /pmc/articles/PMC7082249/ /pubmed/32206584 http://dx.doi.org/10.21037/tp.2019.09.09 Text en 2020 Translational Pediatrics. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) .
spellingShingle Review Article
Hodges, Holly
Fealko, Casey
Soares, Neelkamal
Autism spectrum disorder: definition, epidemiology, causes, and clinical evaluation
title Autism spectrum disorder: definition, epidemiology, causes, and clinical evaluation
title_full Autism spectrum disorder: definition, epidemiology, causes, and clinical evaluation
title_fullStr Autism spectrum disorder: definition, epidemiology, causes, and clinical evaluation
title_full_unstemmed Autism spectrum disorder: definition, epidemiology, causes, and clinical evaluation
title_short Autism spectrum disorder: definition, epidemiology, causes, and clinical evaluation
title_sort autism spectrum disorder: definition, epidemiology, causes, and clinical evaluation
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082249/
https://www.ncbi.nlm.nih.gov/pubmed/32206584
http://dx.doi.org/10.21037/tp.2019.09.09
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