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Autism spectrum disorder: definition, epidemiology, causes, and clinical evaluation
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social communication and the presence of restricted interests and repetitive behaviors. There have been recent concerns about increased prevalence, and this article seeks to elaborate on factors that may inf...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082249/ https://www.ncbi.nlm.nih.gov/pubmed/32206584 http://dx.doi.org/10.21037/tp.2019.09.09 |
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author | Hodges, Holly Fealko, Casey Soares, Neelkamal |
author_facet | Hodges, Holly Fealko, Casey Soares, Neelkamal |
author_sort | Hodges, Holly |
collection | PubMed |
description | Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social communication and the presence of restricted interests and repetitive behaviors. There have been recent concerns about increased prevalence, and this article seeks to elaborate on factors that may influence prevalence rates, including recent changes to the diagnostic criteria. The authors review evidence that ASD is a neurobiological disorder influenced by both genetic and environmental factors affecting the developing brain, and enumerate factors that correlate with ASD risk. Finally, the article describes how clinical evaluation begins with developmental screening, followed by referral for a definitive diagnosis, and provides guidance on screening for comorbid conditions. |
format | Online Article Text |
id | pubmed-7082249 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | AME Publishing Company |
record_format | MEDLINE/PubMed |
spelling | pubmed-70822492020-03-23 Autism spectrum disorder: definition, epidemiology, causes, and clinical evaluation Hodges, Holly Fealko, Casey Soares, Neelkamal Transl Pediatr Review Article Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social communication and the presence of restricted interests and repetitive behaviors. There have been recent concerns about increased prevalence, and this article seeks to elaborate on factors that may influence prevalence rates, including recent changes to the diagnostic criteria. The authors review evidence that ASD is a neurobiological disorder influenced by both genetic and environmental factors affecting the developing brain, and enumerate factors that correlate with ASD risk. Finally, the article describes how clinical evaluation begins with developmental screening, followed by referral for a definitive diagnosis, and provides guidance on screening for comorbid conditions. AME Publishing Company 2020-02 /pmc/articles/PMC7082249/ /pubmed/32206584 http://dx.doi.org/10.21037/tp.2019.09.09 Text en 2020 Translational Pediatrics. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) . |
spellingShingle | Review Article Hodges, Holly Fealko, Casey Soares, Neelkamal Autism spectrum disorder: definition, epidemiology, causes, and clinical evaluation |
title | Autism spectrum disorder: definition, epidemiology, causes, and clinical evaluation |
title_full | Autism spectrum disorder: definition, epidemiology, causes, and clinical evaluation |
title_fullStr | Autism spectrum disorder: definition, epidemiology, causes, and clinical evaluation |
title_full_unstemmed | Autism spectrum disorder: definition, epidemiology, causes, and clinical evaluation |
title_short | Autism spectrum disorder: definition, epidemiology, causes, and clinical evaluation |
title_sort | autism spectrum disorder: definition, epidemiology, causes, and clinical evaluation |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082249/ https://www.ncbi.nlm.nih.gov/pubmed/32206584 http://dx.doi.org/10.21037/tp.2019.09.09 |
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