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Dynamic changes of acquired T790M mutation and small cell lung cancer transformation in a patient with EGFR-mutant adenocarcinoma after first- and third-generation EGFR-TKIs: a case report

Epithelial growth factor receptor (EGFR) T790M mutation and small cell lung cancer (SCLC) transformation are well-known resistance mechanisms acquired during treatment with EGFR tyrosine kinase inhibitors (TKIs). Various mechanisms sometimes coexist in patients. Here, we report a 57-year-old female...

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Detalles Bibliográficos
Autores principales: Ma, Shuxiang, He, Zhen, Fu, Hongyong, Wang, Lili, Wu, Xuan, Zhang, Zhe, Wang, Qiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082284/
https://www.ncbi.nlm.nih.gov/pubmed/32206560
http://dx.doi.org/10.21037/tlcr.2020.01.07