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Image-Based Dynamic Phenotyping Reveals Genetic Determinants of Filamentation-Mediated β-Lactam Tolerance
Antibiotic tolerance characterized by slow killing of bacteria in response to a drug can lead to treatment failure and promote the emergence of resistance. β-lactam antibiotics inhibit cell wall growth in bacteria and many of them cause filamentation followed by cell lysis. Hence delayed cell lysis...
Autores principales: | Zahir, Taiyeb, Wilmaerts, Dorien, Franke, Sabine, Weytjens, Bram, Camacho, Rafael, Marchal, Kathleen, Hofkens, Johan, Fauvart, Maarten, Michiels, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082316/ https://www.ncbi.nlm.nih.gov/pubmed/32231648 http://dx.doi.org/10.3389/fmicb.2020.00374 |
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