B7-Positive and B7-Negative Acute Myeloid Leukemias Display Distinct T Cell Maturation Profiles, Immune Checkpoint Receptor Expression, and European Leukemia Net Risk Profiles

Acute myeloid leukemia (AML) is generally considered a poorly immunogenic malignancy, displaying a “non-inflamed” leukemia microenvironment (LME), leading to T cell tolerance. However, the immune landscape of AML is much more heterogeneous. Since B7 expression is regarded as a consequence of an inte...

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Detalles Bibliográficos
Autores principales: Antohe, Ion, Dǎscǎlescu, Angela, Dǎnǎilǎ, Cǎtǎlin, Titieanu, Amalia, Zlei, Mihaela, Ivanov, Iuliu, Sireteanu, Adriana, Pavel, Mariana, Cianga, Petru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082324/
https://www.ncbi.nlm.nih.gov/pubmed/32231996
http://dx.doi.org/10.3389/fonc.2020.00264

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