X-ray tomography of cryopreserved human prostate cancer cells: mitochondrial targeting by an organoiridium photosensitiser

ABSTRACT: The organoiridium complex Ir[(C,N)(2)(O,O)] (1) where C, N = 1-phenylisoquinoline and O,O = 2,2,6,6-tetramethyl-3,5-heptanedionate is a promising photosensitiser for Photo-Dynamic Therapy (PDT). 1 is not toxic to cells in the dark. However, irradiation of the compound with one-photon blue...

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Detalles Bibliográficos
Autores principales: Bolitho, Elizabeth M., Sanchez-Cano, Carlos, Huang, Huaiyi, Hands-Portman, Ian, Spink, Matthew, Quinn, Paul D., Harkiolaki, Maria, Sadler, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082392/
https://www.ncbi.nlm.nih.gov/pubmed/32124100
http://dx.doi.org/10.1007/s00775-020-01761-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082392/
https://www.ncbi.nlm.nih.gov/pubmed/32124100
http://dx.doi.org/10.1007/s00775-020-01761-8

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