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Aspergillus fumigatus Mitochondrial Acetyl Coenzyme A Acetyltransferase as an Antifungal Target

Ergosterol plays an important role in maintaining cell membrane sterol homeostasis in fungi, and as such, it is considered an effective target in antifungal chemotherapy. In yeast, the enzyme acetyl-coenzyme A (CoA) acetyltransferase (ERG10) catalyzes the Claisen condensation of two acetyl-CoA molec...

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Detalles Bibliográficos
Autores principales:	Zhang, Yuanwei, Wei, Wenfan, Fan, Jialu, Jin, Cheng, Lu, Ling, Fang, Wenxia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2020
Materias:	Public and Environmental Health Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082573/ https://www.ncbi.nlm.nih.gov/pubmed/32005728 http://dx.doi.org/10.1128/AEM.02986-19

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