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Recurrent endometrial stromal sarcoma in the abdominal wall following a total hysterectomy: A rare case report
INTRODUCTION: High-grade endometrial stromal sarcoma (HG-ESS) is a rare pathological type of uterine sarcoma. Over 80 % of affected patients would experience recurrences within a few years of initial presentation. Such case is rare and therefore, we need to report the case including the management....
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082597/ https://www.ncbi.nlm.nih.gov/pubmed/32197223 http://dx.doi.org/10.1016/j.ijscr.2020.03.003 |
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author | Purbadi, Sigit Saspriyana, Kade Yudi |
author_facet | Purbadi, Sigit Saspriyana, Kade Yudi |
author_sort | Purbadi, Sigit |
collection | PubMed |
description | INTRODUCTION: High-grade endometrial stromal sarcoma (HG-ESS) is a rare pathological type of uterine sarcoma. Over 80 % of affected patients would experience recurrences within a few years of initial presentation. Such case is rare and therefore, we need to report the case including the management. Information on performing good surgical techniques is important. CASE PRESENTATION: A 55-year-old female patient was referred after having a total hysterectomy and bilateral salphingoophorectomy at a private hospital. Results of pathologic examination showed that the patient had HG-ESS. The patient subsequently received adjuvant chemotherapy. The regimens used were Carboplatin (AUC-6) and Paclitaxel (175 mg/m(2)). Within five months following the chemotherapy, she complained rapid abdominal enlargement, which was a clinically mobile palpable solid mass at the level of the navel. Imaging findings suggested recurrent endometrial stromal sarcoma in the abdominal wall. Wide excision and frozen section, which were continued with mesh insertion and abdominal wall reconstruction, were then performed. DISCUSSION: Recurrence develops in one-half to two-third of patients with HG-ESS. It has been reported that the sites of recurrence usually include multiple lung metastases, peritoneal metastases, and/or local recurrences. There is currently no standard therapy for patients with recurrence of the disease as HG-ESS is a rare clinical entity. Treatment has been defined based on experiences gained from retrospective case reports. CONCLUSION: Successful management of patients with recurrent abdominal wall HG-ESS requires interdisciplinary and interprofessional teamwork. Multi-centre prospective trials are required to develop a guideline of optimal treatment for the disease entity, particularly the recurrence. |
format | Online Article Text |
id | pubmed-7082597 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-70825972020-03-24 Recurrent endometrial stromal sarcoma in the abdominal wall following a total hysterectomy: A rare case report Purbadi, Sigit Saspriyana, Kade Yudi Int J Surg Case Rep Article INTRODUCTION: High-grade endometrial stromal sarcoma (HG-ESS) is a rare pathological type of uterine sarcoma. Over 80 % of affected patients would experience recurrences within a few years of initial presentation. Such case is rare and therefore, we need to report the case including the management. Information on performing good surgical techniques is important. CASE PRESENTATION: A 55-year-old female patient was referred after having a total hysterectomy and bilateral salphingoophorectomy at a private hospital. Results of pathologic examination showed that the patient had HG-ESS. The patient subsequently received adjuvant chemotherapy. The regimens used were Carboplatin (AUC-6) and Paclitaxel (175 mg/m(2)). Within five months following the chemotherapy, she complained rapid abdominal enlargement, which was a clinically mobile palpable solid mass at the level of the navel. Imaging findings suggested recurrent endometrial stromal sarcoma in the abdominal wall. Wide excision and frozen section, which were continued with mesh insertion and abdominal wall reconstruction, were then performed. DISCUSSION: Recurrence develops in one-half to two-third of patients with HG-ESS. It has been reported that the sites of recurrence usually include multiple lung metastases, peritoneal metastases, and/or local recurrences. There is currently no standard therapy for patients with recurrence of the disease as HG-ESS is a rare clinical entity. Treatment has been defined based on experiences gained from retrospective case reports. CONCLUSION: Successful management of patients with recurrent abdominal wall HG-ESS requires interdisciplinary and interprofessional teamwork. Multi-centre prospective trials are required to develop a guideline of optimal treatment for the disease entity, particularly the recurrence. Elsevier 2020-03-07 /pmc/articles/PMC7082597/ /pubmed/32197223 http://dx.doi.org/10.1016/j.ijscr.2020.03.003 Text en © 2020 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Purbadi, Sigit Saspriyana, Kade Yudi Recurrent endometrial stromal sarcoma in the abdominal wall following a total hysterectomy: A rare case report |
title | Recurrent endometrial stromal sarcoma in the abdominal wall following a total hysterectomy: A rare case report |
title_full | Recurrent endometrial stromal sarcoma in the abdominal wall following a total hysterectomy: A rare case report |
title_fullStr | Recurrent endometrial stromal sarcoma in the abdominal wall following a total hysterectomy: A rare case report |
title_full_unstemmed | Recurrent endometrial stromal sarcoma in the abdominal wall following a total hysterectomy: A rare case report |
title_short | Recurrent endometrial stromal sarcoma in the abdominal wall following a total hysterectomy: A rare case report |
title_sort | recurrent endometrial stromal sarcoma in the abdominal wall following a total hysterectomy: a rare case report |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082597/ https://www.ncbi.nlm.nih.gov/pubmed/32197223 http://dx.doi.org/10.1016/j.ijscr.2020.03.003 |
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