p-Pyridinyl oxime carbamates: synthesis, DNA binding, DNA photocleaving activity and theoretical photodegradation studies

A number of p-pyridinyl oxime carbamate derivatives were prepared upon the reaction of the corresponding oximes with isocyanates. These novel compounds reacted photochemically in the presence of supercoiled plasmid DNA. Structure–activity relationship (SAR) studies revealed that the substituent on t...

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Detalles Bibliográficos
Autores principales: Gritzapis, Panagiotis S, Varras, Panayiotis C, Andreou, Nikolaos-Panagiotis, Katsani, Katerina R, Dafnopoulos, Konstantinos, Psomas, George, Peitsinis, Zisis V, Koumbis, Alexandros E, Fylaktakidou, Konstantina C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2020
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082612/
https://www.ncbi.nlm.nih.gov/pubmed/32256851
http://dx.doi.org/10.3762/bjoc.16.33

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