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PD98059 Protects Cerebral Cortex Mitochondrial Structure and Function at 48 h Post-Resuscitation in a Rat Model of Cardiac Arrest

BACKGROUND: Mitochondria play a critical role as effectors and targets of brain injury in the post-resuscitation period. Although we found previously that the extracellular signal-regulated kinase (ERK)1/2 inhibitor PD98059 (PD) protects the brain against mitochondrial-mediated cell death at 24 h po...

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Detalles Bibliográficos
Autores principales:	Zheng, Jun-Hui, Chen, Meng-Hua, Fu, Zhao-Yin, Li, Nuo, Xie, Lu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082620/ https://www.ncbi.nlm.nih.gov/pubmed/32214796 http://dx.doi.org/10.2147/DDDT.S231980

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