Cargando…
Multifunctional Immunoliposomes Combining Catalase and PD-L1 Antibodies Overcome Tumor Hypoxia and Enhance Immunotherapeutic Effects Against Melanoma
BACKGROUND: Immune checkpoint blockades (ICBs) are a promising treatment for cancers such as melanoma by blocking important inhibitory pathways that enable tumor cells to evade immune attack. Programmed death ligand 1 monoclonal antibodies (aPDL1s) can be used as an ICB to significantly enhance the...
Autores principales: | Hei, Yu, Teng, Binhong, Zeng, Ziqian, Zhang, Siqi, Li, Qian, Pan, Jijia, Luo, Zuyuan, Xiong, Chunyang, Wei, Shicheng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082626/ https://www.ncbi.nlm.nih.gov/pubmed/32214807 http://dx.doi.org/10.2147/IJN.S225807 |
Ejemplares similares
-
Dual activity of PD-L1 targeted Doxorubicin immunoliposomes promoted an enhanced efficacy of the antitumor immune response in melanoma murine model
por: Merino, María, et al.
Publicado: (2021) -
Targeting immunoliposomes to EGFR-positive glioblastoma
por: Kasenda, B., et al.
Publicado: (2022) -
Immunoliposomes for detection of rupture-prone intracranial aneurysms
por: Jahromi, Behnam Rezai, et al.
Publicado: (2023) -
Targeting melanoma with immunoliposomes coupled to anti-MAGE A1 TCR-like single-chain antibody
por: Saeed, Mesha, et al.
Publicado: (2016) -
Immunoliposomes doubly targeted to transferrin receptor and to α-synuclein
por: Loureiro, Joana A, et al.
Publicado: (2015)