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Comprehensive chemical proteomics for target deconvolution of the redox active drug auranofin

Chemical proteomics encompasses novel drug target deconvolution methods in which compound modification is not required. Herein we use Thermal Proteome Profiling, Functional Identification of Target by Expression Proteomics and multiplexed redox proteomics for deconvolution of auranofin targets to ai...

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Detalles Bibliográficos
Autores principales:	Saei, Amir Ata, Gullberg, Hjalmar, Sabatier, Pierre, Beusch, Christian M., Johansson, Katarina, Lundgren, Bo, Arvidsson, Per I., Arnér, Elias S.J., Zubarev, Roman A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082630/ https://www.ncbi.nlm.nih.gov/pubmed/32199331 http://dx.doi.org/10.1016/j.redox.2020.101491

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