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Saturated Fat Is More Metabolically Harmful for the Human Liver Than Unsaturated Fat or Simple Sugars

OBJECTIVE: Nonalcoholic fatty liver disease (i.e., increased intrahepatic triglyceride [IHTG] content), predisposes to type 2 diabetes and cardiovascular disease. Adipose tissue lipolysis and hepatic de novo lipogenesis (DNL) are the main pathways contributing to IHTG. We hypothesized that dietary m...

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Detalles Bibliográficos
Autores principales: Luukkonen, Panu K., Sädevirta, Sanja, Zhou, You, Kayser, Brandon, Ali, Ashfaq, Ahonen, Linda, Lallukka, Susanna, Pelloux, Véronique, Gaggini, Melania, Jian, Ching, Hakkarainen, Antti, Lundbom, Nina, Gylling, Helena, Salonen, Anne, Orešič, Matej, Hyötyläinen, Tuulia, Orho-Melander, Marju, Rissanen, Aila, Gastaldelli, Amalia, Clément, Karine, Hodson, Leanne, Yki-Järvinen, Hannele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082640/
https://www.ncbi.nlm.nih.gov/pubmed/29844096
http://dx.doi.org/10.2337/dc18-0071