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Hazards of Using Masking Protocols When Performing Ligand Binding Assays: Lessons From the Sigma-1 and Sigma-2 Receptors

Sigma-1 and sigma-2 receptors are emerging therapeutic targets. Although the molecular identity of the sigma-2 receptor has recently been determined, receptor quantitation has used, and continues to use, the sigma-1 selective agents (+) pentazocine or dextrallorphan to mask the sigma-1 receptor in r...

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Detalles Bibliográficos
Autores principales:	Abbas, Haider, Borde, Preeti, Willars, Gary B., Ferry, David R., Safrany, Stephen T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082753/ https://www.ncbi.nlm.nih.gov/pubmed/32231573 http://dx.doi.org/10.3389/fphar.2020.00309

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