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A combination of the activation marker CD86 and the immune checkpoint marker B and T lymphocyte attenuator (BTLA) indicates a putative permissive activation state of B cell subtypes in healthy blood donors independent of age and sex
BACKGROUND: The use of anti-B cell based therapies in immune-mediated diseases targeting general B cell markers or molecules important for B cell function has increased the clinical needs of monitoring B cell subpopulations. RESULTS: We analyzed the expression profile of cell surface markers CD86 an...
Autores principales: | Axelsson, Susanne, Magnuson, Anders, Lange, Anna, Alshamari, Aseel, Hörnquist, Elisabeth Hultgren, Hultgren, Olof |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082969/ https://www.ncbi.nlm.nih.gov/pubmed/32197584 http://dx.doi.org/10.1186/s12865-020-00343-2 |
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