Characterization of astrocytes throughout life in wildtype and APP/PS1 mice after early-life stress exposure

BACKGROUND: Early-life stress (ES) is an emerging risk factor for later life development of Alzheimer’s disease (AD). We have previously shown that ES modulates amyloid-beta pathology and the microglial response to it in the APPswe/PS1dE9 mouse model. Because astrocytes are key players in the pathog...

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Detalles Bibliográficos
Autores principales: Abbink, Maralinde R., Kotah, Janssen M., Hoeijmakers, Lianne, Mak, Aline, Yvon-Durocher, Genevieve, van der Gaag, Bram, Lucassen, Paul J., Korosi, Aniko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083036/
https://www.ncbi.nlm.nih.gov/pubmed/32197653
http://dx.doi.org/10.1186/s12974-020-01762-z

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