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Mammalian RNA Decay Pathways Are Highly Specialized and Widely Linked to Translation

RNA decay is crucial for mRNA turnover and surveillance and misregulated in many diseases. This complex system is challenging to study, particularly in mammals, where it remains unclear whether decay pathways perform specialized versus redundant roles. Cytoplasmic pathways and links to translation a...

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Detalles Bibliográficos
Autores principales: Tuck, Alex Charles, Rankova, Aneliya, Arpat, Alaaddin Bulak, Liechti, Luz Angelica, Hess, Daniel, Iesmantavicius, Vytautas, Castelo-Szekely, Violeta, Gatfield, David, Bühler, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083229/
https://www.ncbi.nlm.nih.gov/pubmed/32048998
http://dx.doi.org/10.1016/j.molcel.2020.01.007