Pseudomonas aeruginosa in the ICU: prevalence, resistance profile, and antimicrobial consumption

INTRODUCTION: Pseudomonas aeruginosa is one of the main pathogens causing infection in intensive care units (ICUs) and usually presents antimicrobial resistance. METHODS: Data were obtained from ICUs between 2010 and 2013. RESULTS: P. aeruginosa had a prevalence of 14.5% of which 48.7% were multidru...

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Detalles Bibliográficos
Autores principales: Ribeiro, Ághata Cardoso da Silva, Crozatti, Márcia Terezinha Lonardoni, da Silva, Adilson Aderito, Macedo, Rodrigo Spineli, Machado, Antonia Maria de Oliveira, Silva, Antonio Távora de Albuquerque
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical - SBMT 2019
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083346/
https://www.ncbi.nlm.nih.gov/pubmed/31859938
http://dx.doi.org/10.1590/0037-8682-0498-2018
Descripción
Sumario:INTRODUCTION: Pseudomonas aeruginosa is one of the main pathogens causing infection in intensive care units (ICUs) and usually presents antimicrobial resistance. METHODS: Data were obtained from ICUs between 2010 and 2013. RESULTS: P. aeruginosa had a prevalence of 14.5% of which 48.7% were multidrug resistant. We observed increasing resistance to carbapenems and polymyxin B and growing consumption of aminoglycosides, meropenem, ceftazidime, and polymyxin B. The regression impact between resistance and consumption was significant with respect to amikacin, imipenem, meropenem, and polymyxin B. CONCLUSIONS: Monitoring antimicrobial consumption and resistant microorganisms should be reinforced to combat antimicrobial- and multi-drug resistance.

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