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In vitro characterization of virulence factors among species of the Candida parapsilosis complex
INTRODUCTION: Candida parapsilosis complex species differ from each other with regard to their prevalence and virulence. METHODS: The hydrolytic enzyme activity, biofilm production, and adhesion to epithelial cells were analyzed in 87 C. parapsilosis complex strains. RESULTS: Among the studied isola...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Sociedade Brasileira de Medicina Tropical - SBMT
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083369/ https://www.ncbi.nlm.nih.gov/pubmed/31994664 http://dx.doi.org/10.1590/0037-8682-0336-2019 |
| _version_ | 1783508518712639488 |
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| author | Ataides, Fábio Silvestre Costa, Carolina Rodrigues Santos, Andressa Santana Freitas, Vivianny Aparecida Queiroz Silva, Thaisa Cristina Zara, Ana Laura Sene Amâncio Jesuino, Rosália Santos Amorim Silva, Maria Rosário Rodrigues |
| author_facet | Ataides, Fábio Silvestre Costa, Carolina Rodrigues Santos, Andressa Santana Freitas, Vivianny Aparecida Queiroz Silva, Thaisa Cristina Zara, Ana Laura Sene Amâncio Jesuino, Rosália Santos Amorim Silva, Maria Rosário Rodrigues |
| author_sort | Ataides, Fábio Silvestre |
| collection | PubMed |
| description | INTRODUCTION: Candida parapsilosis complex species differ from each other with regard to their prevalence and virulence. METHODS: The hydrolytic enzyme activity, biofilm production, and adhesion to epithelial cells were analyzed in 87 C. parapsilosis complex strains. RESULTS: Among the studied isolates, 97.7%, 63.2%, and 82.8% exhibited very strong proteinase, esterase, and hemolysin activity, respectively. All the C. parapsilosis complex isolates produced biofilms and presented an average adherence of 96.0 yeasts/100 epithelial cells. CONCLUSIONS: Our results show that Candida parapsilosis complex isolates showed different levels of enzyme activity, biofilm production, and adhesion to epithelial cells. |
| format | Online Article Text |
| id | pubmed-7083369 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2020 |
| publisher | Sociedade Brasileira de Medicina Tropical - SBMT |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-70833692020-03-25 In vitro characterization of virulence factors among species of the Candida parapsilosis complex Ataides, Fábio Silvestre Costa, Carolina Rodrigues Santos, Andressa Santana Freitas, Vivianny Aparecida Queiroz Silva, Thaisa Cristina Zara, Ana Laura Sene Amâncio Jesuino, Rosália Santos Amorim Silva, Maria Rosário Rodrigues Rev Soc Bras Med Trop Short Communication INTRODUCTION: Candida parapsilosis complex species differ from each other with regard to their prevalence and virulence. METHODS: The hydrolytic enzyme activity, biofilm production, and adhesion to epithelial cells were analyzed in 87 C. parapsilosis complex strains. RESULTS: Among the studied isolates, 97.7%, 63.2%, and 82.8% exhibited very strong proteinase, esterase, and hemolysin activity, respectively. All the C. parapsilosis complex isolates produced biofilms and presented an average adherence of 96.0 yeasts/100 epithelial cells. CONCLUSIONS: Our results show that Candida parapsilosis complex isolates showed different levels of enzyme activity, biofilm production, and adhesion to epithelial cells. Sociedade Brasileira de Medicina Tropical - SBMT 2020-01-27 /pmc/articles/PMC7083369/ /pubmed/31994664 http://dx.doi.org/10.1590/0037-8682-0336-2019 Text en https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License |
| spellingShingle | Short Communication Ataides, Fábio Silvestre Costa, Carolina Rodrigues Santos, Andressa Santana Freitas, Vivianny Aparecida Queiroz Silva, Thaisa Cristina Zara, Ana Laura Sene Amâncio Jesuino, Rosália Santos Amorim Silva, Maria Rosário Rodrigues In vitro characterization of virulence factors among species of the Candida parapsilosis complex |
| title |
In vitro characterization of virulence factors among species of
the Candida parapsilosis complex |
| title_full |
In vitro characterization of virulence factors among species of
the Candida parapsilosis complex |
| title_fullStr |
In vitro characterization of virulence factors among species of
the Candida parapsilosis complex |
| title_full_unstemmed |
In vitro characterization of virulence factors among species of
the Candida parapsilosis complex |
| title_short |
In vitro characterization of virulence factors among species of
the Candida parapsilosis complex |
| title_sort | in vitro characterization of virulence factors among species of
the candida parapsilosis complex |
| topic | Short Communication |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083369/ https://www.ncbi.nlm.nih.gov/pubmed/31994664 http://dx.doi.org/10.1590/0037-8682-0336-2019 |
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