Hepatitis B: Prevalence and occult infection in HIV-infected patients

INTRODUCTION: HBV and HIV have identical transmission routes. The aim of this study was to determine the prevalence of HBV in HIV patients and to detect the presence of occult HBV infection. METHODS: All samples were tested for serology markers and using qPCR. RESULTS: This study included 232 indivi...

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Autores principales: Calux, Samira Julien, Silva, Vanessa Cristina Martins, Compri, Adriana Parise, Lemos, Marcílio Figueiredo, Santos, Ana Paula de Torres, Oba, Isabel Takano, Mendes-Correa, Maria Cássia J., Moreira, Regina Célia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical - SBMT 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083387/
https://www.ncbi.nlm.nih.gov/pubmed/31994654
http://dx.doi.org/10.1590/0037-8682-0533-2018
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author Calux, Samira Julien
Silva, Vanessa Cristina Martins
Compri, Adriana Parise
Lemos, Marcílio Figueiredo
Santos, Ana Paula de Torres
Oba, Isabel Takano
Mendes-Correa, Maria Cássia J.
Moreira, Regina Célia
author_facet Calux, Samira Julien
Silva, Vanessa Cristina Martins
Compri, Adriana Parise
Lemos, Marcílio Figueiredo
Santos, Ana Paula de Torres
Oba, Isabel Takano
Mendes-Correa, Maria Cássia J.
Moreira, Regina Célia
author_sort Calux, Samira Julien
collection PubMed
description INTRODUCTION: HBV and HIV have identical transmission routes. The aim of this study was to determine the prevalence of HBV in HIV patients and to detect the presence of occult HBV infection. METHODS: All samples were tested for serology markers and using qPCR. RESULTS: This study included 232 individuals, out of which 36.6% presented with HBV markers and 11.8% presented with HBsAg or HBV-DNA, including 3 patients that showed OBI. CONCLUSIONS: We observed a high prevalence of HBV among HIV patients. In addition, the results suggest that OBI can occur in patients with serological profiles that are indicative of past infection. Therefore, the application of molecular tests may enable the identification of infections that are not evident solely based on serology.
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spelling pubmed-70833872020-03-25 Hepatitis B: Prevalence and occult infection in HIV-infected patients Calux, Samira Julien Silva, Vanessa Cristina Martins Compri, Adriana Parise Lemos, Marcílio Figueiredo Santos, Ana Paula de Torres Oba, Isabel Takano Mendes-Correa, Maria Cássia J. Moreira, Regina Célia Rev Soc Bras Med Trop Short Communication INTRODUCTION: HBV and HIV have identical transmission routes. The aim of this study was to determine the prevalence of HBV in HIV patients and to detect the presence of occult HBV infection. METHODS: All samples were tested for serology markers and using qPCR. RESULTS: This study included 232 individuals, out of which 36.6% presented with HBV markers and 11.8% presented with HBsAg or HBV-DNA, including 3 patients that showed OBI. CONCLUSIONS: We observed a high prevalence of HBV among HIV patients. In addition, the results suggest that OBI can occur in patients with serological profiles that are indicative of past infection. Therefore, the application of molecular tests may enable the identification of infections that are not evident solely based on serology. Sociedade Brasileira de Medicina Tropical - SBMT 2020-01-27 /pmc/articles/PMC7083387/ /pubmed/31994654 http://dx.doi.org/10.1590/0037-8682-0533-2018 Text en https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Short Communication
Calux, Samira Julien
Silva, Vanessa Cristina Martins
Compri, Adriana Parise
Lemos, Marcílio Figueiredo
Santos, Ana Paula de Torres
Oba, Isabel Takano
Mendes-Correa, Maria Cássia J.
Moreira, Regina Célia
Hepatitis B: Prevalence and occult infection in HIV-infected patients
title Hepatitis B: Prevalence and occult infection in HIV-infected patients
title_full Hepatitis B: Prevalence and occult infection in HIV-infected patients
title_fullStr Hepatitis B: Prevalence and occult infection in HIV-infected patients
title_full_unstemmed Hepatitis B: Prevalence and occult infection in HIV-infected patients
title_short Hepatitis B: Prevalence and occult infection in HIV-infected patients
title_sort hepatitis b: prevalence and occult infection in hiv-infected patients
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083387/
https://www.ncbi.nlm.nih.gov/pubmed/31994654
http://dx.doi.org/10.1590/0037-8682-0533-2018
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