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Evidence of a sylvatic enzootic cycle of Leishmania infantum in the State of Amapá, Brazil

INTRODUCTION: Leishmania infantum was considered to be absent from Amapá until 2017 when canine infection was detected. However, there is a lack of knowledge about which reservoir species are involved in transmission in this region. METHODS: Between 2014 and 2016, 86 samples from wild mammals and 74...

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Detalles Bibliográficos
Autores principales: Moreno, Eduardo Stramandinoli, Sabioni, Luiz Alberto, de Seixas, Marina Maria Moraes, de Souza, Job Alves, Marcelino, Andreza Pain, Shimabukuro, Paloma Helena Fernandes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical - SBMT 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083388/
https://www.ncbi.nlm.nih.gov/pubmed/31859944
http://dx.doi.org/10.1590/0037-8682-0169-2019
Descripción
Sumario:INTRODUCTION: Leishmania infantum was considered to be absent from Amapá until 2017 when canine infection was detected. However, there is a lack of knowledge about which reservoir species are involved in transmission in this region. METHODS: Between 2014 and 2016, 86 samples from wild mammals and 74 from domestic dogs were collected in Wajãpi Indigenous Territory and were tested for the presence of deoxyribonucleic acid (DNA) of Leishmania. RESULTS: The DNA of Le. infantum was detected in two rodent samples, Dasyprocta sp. and Proechimys cuvieri. CONCLUSIONS: This is the first evidence characterizing a sylvatic transmission cycle of Le. infantum in the State of Amapá.