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pH-Responsive Artesunate Polymer Prodrugs with Enhanced Ablation Effect on Rodent Xenograft Colon Cancer

PURPOSE: In this study, pH-sensitive poly(2-ethyl-2-oxazoline)-poly(lactic acid)-poly(β-amino ester) (PEOz-PLA-PBAE) triblock copolymers were synthesized and were conjugated with an antimalaria drug artesunate (ART), for inhibition of a colon cancer xenograft model. METHODS: The as-prepared polymer...

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Detalles Bibliográficos
Autores principales:	Hao, Dan-Li, Xie, Ran, De, Ge-Jing, Yi, Hong, Zang, Chen, Yang, Mi-Yi, Liu, Li, Ma, Hai, Cai, Wei-Yan, Zhao, Qing-He, Sui, Feng, Chen, Yan-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083641/ https://www.ncbi.nlm.nih.gov/pubmed/32214810 http://dx.doi.org/10.2147/IJN.S242032

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