Therapeutic effects of the PKR inhibitor C16 suppressing tumor proliferation and angiogenesis in hepatocellular carcinoma in vitro and in vivo

The therapeutic effects of C16, which is an inhibitor of RNA-dependent protein kinase (PKR), on growth of hepatocellular carcinoma (HCC) cells and tumor progression in vitro and in vivo were evaluated. Huh7 cells, a human HCC cell line, were used. The effects of C16 on cell viability were evaluated...

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Detalles Bibliográficos
Autores principales: Watanabe, Takao, Ninomiya, Hiroko, Saitou, Takashi, Takanezawa, Sota, Yamamoto, Shin, Imai, Yusuke, Yoshida, Osamu, Kawakami, Ryosuke, Hirooka, Masashi, Abe, Masanori, Imamura, Takeshi, Hiasa, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083831/
https://www.ncbi.nlm.nih.gov/pubmed/32198380
http://dx.doi.org/10.1038/s41598-020-61579-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083831/
https://www.ncbi.nlm.nih.gov/pubmed/32198380
http://dx.doi.org/10.1038/s41598-020-61579-x

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