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Structural analysis of TIFA: Insight into TIFA-dependent signal transduction in innate immunity

TRAF-interacting protein with a forkhead-associated (FHA) domain (TIFA), originally identified as an adaptor protein of TRAF6, has recently been shown to be involved in innate immunity, induced by a pathogen-associated molecular pattern (PAMP). ADP-β-D-manno-heptose, a newly identified PAMP, binds t...

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Detalles Bibliográficos
Autores principales:	Nakamura, Teruya, Hashikawa, Chie, Okabe, Kohtaro, Yokote, Yuya, Chirifu, Mami, Toma-Fukai, Sachiko, Nakamura, Narushi, Matsuo, Mihoko, Kamikariya, Miho, Okamoto, Yoshinari, Gohda, Jin, Akiyama, Taishin, Semba, Kentaro, Ikemizu, Shinji, Otsuka, Masami, Inoue, Jun-ichiro, Yamagata, Yuriko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083832/ https://www.ncbi.nlm.nih.gov/pubmed/32198460 http://dx.doi.org/10.1038/s41598-020-61972-6

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