A simple method to monitor hemolysis in real time

Blood damage (hemolysis) can occur during clinical procedures, e.g. dialysis, due to human error or faulty equipment, and it can cause significant harm to the patient or even death. We propose a simple technique to monitor changes in hemolysis levels continuously and in real time. As red blood cells...

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Detalles Bibliográficos
Autores principales: Van Buren, Tyler, Arwatz, Gilad, Smits, Alexander J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083869/
https://www.ncbi.nlm.nih.gov/pubmed/32198369
http://dx.doi.org/10.1038/s41598-020-62041-8
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author Van Buren, Tyler
Arwatz, Gilad
Smits, Alexander J.
author_facet Van Buren, Tyler
Arwatz, Gilad
Smits, Alexander J.
author_sort Van Buren, Tyler
collection PubMed
description Blood damage (hemolysis) can occur during clinical procedures, e.g. dialysis, due to human error or faulty equipment, and it can cause significant harm to the patient or even death. We propose a simple technique to monitor changes in hemolysis levels continuously and in real time. As red blood cells rupture, the overall conductivity of the blood increases. Here, we demonstrate that small changes in porcine blood hemolysis can be detected through a simple resistance measurement.
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spelling pubmed-70838692020-03-26 A simple method to monitor hemolysis in real time Van Buren, Tyler Arwatz, Gilad Smits, Alexander J. Sci Rep Article Blood damage (hemolysis) can occur during clinical procedures, e.g. dialysis, due to human error or faulty equipment, and it can cause significant harm to the patient or even death. We propose a simple technique to monitor changes in hemolysis levels continuously and in real time. As red blood cells rupture, the overall conductivity of the blood increases. Here, we demonstrate that small changes in porcine blood hemolysis can be detected through a simple resistance measurement. Nature Publishing Group UK 2020-03-20 /pmc/articles/PMC7083869/ /pubmed/32198369 http://dx.doi.org/10.1038/s41598-020-62041-8 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Van Buren, Tyler
Arwatz, Gilad
Smits, Alexander J.
A simple method to monitor hemolysis in real time
title A simple method to monitor hemolysis in real time
title_full A simple method to monitor hemolysis in real time
title_fullStr A simple method to monitor hemolysis in real time
title_full_unstemmed A simple method to monitor hemolysis in real time
title_short A simple method to monitor hemolysis in real time
title_sort simple method to monitor hemolysis in real time
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083869/
https://www.ncbi.nlm.nih.gov/pubmed/32198369
http://dx.doi.org/10.1038/s41598-020-62041-8
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