The cryo-EM structure of the SNX–BAR Mvp1 tetramer

Sorting nexins (SNX) are a family of PX domain-containing proteins with pivotal roles in trafficking and signaling. SNX-BARs, which also have a curvature-generating Bin/Amphiphysin/Rvs (BAR) domain, have membrane-remodeling functions, particularly at the endosome. The minimal PX-BAR module is a dime...

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Detalles Bibliográficos
Autores principales: Sun, Dapeng, Varlakhanova, Natalia V., Tornabene, Bryan A., Ramachandran, Rajesh, Zhang, Peijun, Ford, Marijn G. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083883/
https://www.ncbi.nlm.nih.gov/pubmed/32198400
http://dx.doi.org/10.1038/s41467-020-15110-5

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