Therapeutic modulation of phagocytosis in glioblastoma can activate both innate and adaptive antitumour immunity

Tumour cell phagocytosis by antigen presenting cells (APCs) is critical to the generation of antitumour immunity. However, cancer cells can evade phagocytosis by upregulating anti-phagocytosis molecule CD47. Here, we show that CD47 blockade alone is inefficient in stimulating glioma cell phagocytosi...

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Detalles Bibliográficos
Autores principales: von Roemeling, Christina A., Wang, Yifan, Qie, Yaqing, Yuan, Hengfeng, Zhao, Hai, Liu, Xiujie, Yang, Zhaogang, Yang, Mingming, Deng, Weiye, Bruno, Katelyn A., Chan, Charles K., Lee, Andrew S., Rosenfeld, Stephen S., Yun, Kyuson, Johnson, Aaron J., Mitchell, Duane A., Jiang, Wen, Kim, Betty Y. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083893/
https://www.ncbi.nlm.nih.gov/pubmed/32198351
http://dx.doi.org/10.1038/s41467-020-15129-8

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