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Enhanced purification coupled with biophysical analyses shows cross-β structure as a core building block for Streptococcus mutans functional amyloids

Streptococcus mutans is an etiologic agent of human dental caries that forms dental plaque biofilms containing functional amyloids. Three amyloidogenic proteins, P1, WapA, and Smu_63c were previously identified. C123 and AgA are naturally occurring amyloid-forming fragments of P1 and WapA, respectiv...

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Detalles Bibliográficos
Autores principales: Barran-Berdon, Ana L., Ocampo, Sebastian, Haider, Momin, Morales-Aparicio, Joyce, Ottenberg, Gregory, Kendall, Amy, Yarmola, Elena, Mishra, Surabhi, Long, Joanna R., Hagen, Stephen J., Stubbs, Gerald, Brady, L. Jeannine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083922/
https://www.ncbi.nlm.nih.gov/pubmed/32198417
http://dx.doi.org/10.1038/s41598-020-62115-7

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