Long noncoding RNA AGPG regulates PFKFB3-mediated tumor glycolytic reprogramming

Tumor cells often reprogram their metabolism for rapid proliferation. The roles of long noncoding RNAs (lncRNAs) in metabolism remodeling and the underlying mechanisms remain elusive. Through screening, we found that the lncRNA Actin Gamma 1 Pseudogene (AGPG) is required for increased glycolysis act...

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Detalles Bibliográficos
Autores principales: Liu, Jia, Liu, Ze-Xian, Wu, Qi-Nian, Lu, Yun-Xin, Wong, Chau-Wei, Miao, Lei, Wang, Yun, Wang, Zixian, Jin, Ying, He, Ming-Ming, Ren, Chao, Wang, De-Shen, Chen, Dong-Liang, Pu, Heng-Ying, Feng, Lin, Li, Bo, Xie, Dan, Zeng, Mu-Sheng, Huang, Peng, Lin, Aifu, Lin, Dongxin, Xu, Rui-Hua, Ju, Huai-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083971/
https://www.ncbi.nlm.nih.gov/pubmed/32198345
http://dx.doi.org/10.1038/s41467-020-15112-3

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