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Saprochaete Capitata Infection in an 80–Year Old Chronic Obstructive Pulmonary Disease (COPD) Patient: A Case Report

BACKGROUND: The fungal disease caused by invasive fungus Saprochaete capitata is becoming an increasingly popular infection. Fungal pathogens mainly occur in patients with immunocompromised disorders such as hematologic malignancies, acute myeloid leukemia, transplant patients. CASE REPORT: In this...

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Autores principales: Duan, Pham Ngoc, Hung, Nguyen Nhu, Nhu, Phong Tran, Thien, Chu Dinh, Tran, Quang Canh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Republic of Macedonia 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084037/
https://www.ncbi.nlm.nih.gov/pubmed/32215088
http://dx.doi.org/10.3889/oamjms.2019.385
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author Duan, Pham Ngoc
Hung, Nguyen Nhu
Nhu, Phong Tran
Thien, Chu Dinh
Tran, Quang Canh
author_facet Duan, Pham Ngoc
Hung, Nguyen Nhu
Nhu, Phong Tran
Thien, Chu Dinh
Tran, Quang Canh
author_sort Duan, Pham Ngoc
collection PubMed
description BACKGROUND: The fungal disease caused by invasive fungus Saprochaete capitata is becoming an increasingly popular infection. Fungal pathogens mainly occur in patients with immunocompromised disorders such as hematologic malignancies, acute myeloid leukemia, transplant patients. CASE REPORT: In this study, we presented a COPD patient infected with S. capitata. At the first check, the patient showed cough, dyspnea, chest pain on both sides. The clinical laboratory test result was characterized with high White blood cell (12.8 G/L), HIV negative. The X ray showed bronchitis and emphysema. Bronchoscopy illustrated bronchial mucositis. CT scanner demonstrated pneumonia with fuzzy nodular lesions and thick interstitial organization in both lungs. The patient was treated with ciprofloxacin 800 mg/day; cefuroxime 2250 mmg/day. However, the fever appeared 2 weeks thereafter. The S. capitata was discovered in the bronchial fluid. The patient was then treated with fluconazole 400 mg/day for 14 days. At the end of treatment, all signs and symptoms of S. capitata infection disappeared and the patient recovered. CONCLUSION: This case study showed that S. capitata infection can occur in the COPD patients and fluconazole is a pertinent drug for treatment of the infection.
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spelling pubmed-70840372020-03-25 Saprochaete Capitata Infection in an 80–Year Old Chronic Obstructive Pulmonary Disease (COPD) Patient: A Case Report Duan, Pham Ngoc Hung, Nguyen Nhu Nhu, Phong Tran Thien, Chu Dinh Tran, Quang Canh Open Access Maced J Med Sci Basic and Clinical Medical Researches in Vietnam BACKGROUND: The fungal disease caused by invasive fungus Saprochaete capitata is becoming an increasingly popular infection. Fungal pathogens mainly occur in patients with immunocompromised disorders such as hematologic malignancies, acute myeloid leukemia, transplant patients. CASE REPORT: In this study, we presented a COPD patient infected with S. capitata. At the first check, the patient showed cough, dyspnea, chest pain on both sides. The clinical laboratory test result was characterized with high White blood cell (12.8 G/L), HIV negative. The X ray showed bronchitis and emphysema. Bronchoscopy illustrated bronchial mucositis. CT scanner demonstrated pneumonia with fuzzy nodular lesions and thick interstitial organization in both lungs. The patient was treated with ciprofloxacin 800 mg/day; cefuroxime 2250 mmg/day. However, the fever appeared 2 weeks thereafter. The S. capitata was discovered in the bronchial fluid. The patient was then treated with fluconazole 400 mg/day for 14 days. At the end of treatment, all signs and symptoms of S. capitata infection disappeared and the patient recovered. CONCLUSION: This case study showed that S. capitata infection can occur in the COPD patients and fluconazole is a pertinent drug for treatment of the infection. Republic of Macedonia 2019-12-20 /pmc/articles/PMC7084037/ /pubmed/32215088 http://dx.doi.org/10.3889/oamjms.2019.385 Text en Copyright: © 2019 Pham Ngoc Duan, Nguyen Nhu Hung, Phong Tran Nhu, Chu Dinh Thien, Quang Canh Tran. http://creativecommons.org/licenses/CC BY-NC/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0)
spellingShingle Basic and Clinical Medical Researches in Vietnam
Duan, Pham Ngoc
Hung, Nguyen Nhu
Nhu, Phong Tran
Thien, Chu Dinh
Tran, Quang Canh
Saprochaete Capitata Infection in an 80–Year Old Chronic Obstructive Pulmonary Disease (COPD) Patient: A Case Report
title Saprochaete Capitata Infection in an 80–Year Old Chronic Obstructive Pulmonary Disease (COPD) Patient: A Case Report
title_full Saprochaete Capitata Infection in an 80–Year Old Chronic Obstructive Pulmonary Disease (COPD) Patient: A Case Report
title_fullStr Saprochaete Capitata Infection in an 80–Year Old Chronic Obstructive Pulmonary Disease (COPD) Patient: A Case Report
title_full_unstemmed Saprochaete Capitata Infection in an 80–Year Old Chronic Obstructive Pulmonary Disease (COPD) Patient: A Case Report
title_short Saprochaete Capitata Infection in an 80–Year Old Chronic Obstructive Pulmonary Disease (COPD) Patient: A Case Report
title_sort saprochaete capitata infection in an 80–year old chronic obstructive pulmonary disease (copd) patient: a case report
topic Basic and Clinical Medical Researches in Vietnam
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084037/
https://www.ncbi.nlm.nih.gov/pubmed/32215088
http://dx.doi.org/10.3889/oamjms.2019.385
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