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Lung Volume Reduction Surgery in Patients with Heterogenous Emphysema: Selecting Perspective
BACKGROUND: Lung volume reduction surgery (LVRS) was introduced to alleviate clinical conditions in selected patients with heterogenous emphysema. Clarifying the most suitable patients for LVRS remained unclear. AIM: This study was undertaken to specifically analyze the preoperative factor affecting...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Republic of Macedonia
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084044/ https://www.ncbi.nlm.nih.gov/pubmed/32215100 http://dx.doi.org/10.3889/oamjms.2019.841 |
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author | Giang, Nguyen Truong Ngoc, Trung Nguyen Nam, Nguyen Van Nhung, Nguyen Viet Thang, Ta Ba Hung, Dong Khac Bac, Nguyen Duy Toi, Chu Dinh Hung, Pham Ngoc |
author_facet | Giang, Nguyen Truong Ngoc, Trung Nguyen Nam, Nguyen Van Nhung, Nguyen Viet Thang, Ta Ba Hung, Dong Khac Bac, Nguyen Duy Toi, Chu Dinh Hung, Pham Ngoc |
author_sort | Giang, Nguyen Truong |
collection | PubMed |
description | BACKGROUND: Lung volume reduction surgery (LVRS) was introduced to alleviate clinical conditions in selected patients with heterogenous emphysema. Clarifying the most suitable patients for LVRS remained unclear. AIM: This study was undertaken to specifically analyze the preoperative factor affecting to LVRS. METHODS: The prospective study was conducted at 103 Military Hospital between July 2014 and April 2016. Severe heterogenous emphysema patients were selected to participate in the study. The information, spirometry, and body plethysmographic pulmonary function tests in 31 patients who underwent LVRS were compared with postoperative outcomes (changing in FEV1 and CAT scale). RESULTS: Of the 31 patients, there was statistically significant difference in the outcome of functional capacity, lung function between two groups (FEV1 ≤ 50% and > 50%) (∆FEV1: 22.46 vs 18.32%; p = 0.042. ∆ CAT: 6.85 vs 5.07; p = 0.048). Changes of the FEV1 and CAT scale were no statistically significant differences in three groups residual volume. Patients with total lung capacity < 140% had more improved than others (∆FEV1: 23.81 vs 15.1%; p = 0.031). CONCLUSION: Preoperative spirometry and body plethysmographic pulmonary function tests were useful measures to selected severe heterogenous emphysema patients for LVRS. Patients with FEV1 ≤ 50%, TLC in the range of 100-140% should be selected. |
format | Online Article Text |
id | pubmed-7084044 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Republic of Macedonia |
record_format | MEDLINE/PubMed |
spelling | pubmed-70840442020-03-25 Lung Volume Reduction Surgery in Patients with Heterogenous Emphysema: Selecting Perspective Giang, Nguyen Truong Ngoc, Trung Nguyen Nam, Nguyen Van Nhung, Nguyen Viet Thang, Ta Ba Hung, Dong Khac Bac, Nguyen Duy Toi, Chu Dinh Hung, Pham Ngoc Open Access Maced J Med Sci Basic and Clinical Medical Researches in Vietnam BACKGROUND: Lung volume reduction surgery (LVRS) was introduced to alleviate clinical conditions in selected patients with heterogenous emphysema. Clarifying the most suitable patients for LVRS remained unclear. AIM: This study was undertaken to specifically analyze the preoperative factor affecting to LVRS. METHODS: The prospective study was conducted at 103 Military Hospital between July 2014 and April 2016. Severe heterogenous emphysema patients were selected to participate in the study. The information, spirometry, and body plethysmographic pulmonary function tests in 31 patients who underwent LVRS were compared with postoperative outcomes (changing in FEV1 and CAT scale). RESULTS: Of the 31 patients, there was statistically significant difference in the outcome of functional capacity, lung function between two groups (FEV1 ≤ 50% and > 50%) (∆FEV1: 22.46 vs 18.32%; p = 0.042. ∆ CAT: 6.85 vs 5.07; p = 0.048). Changes of the FEV1 and CAT scale were no statistically significant differences in three groups residual volume. Patients with total lung capacity < 140% had more improved than others (∆FEV1: 23.81 vs 15.1%; p = 0.031). CONCLUSION: Preoperative spirometry and body plethysmographic pulmonary function tests were useful measures to selected severe heterogenous emphysema patients for LVRS. Patients with FEV1 ≤ 50%, TLC in the range of 100-140% should be selected. Republic of Macedonia 2019-12-20 /pmc/articles/PMC7084044/ /pubmed/32215100 http://dx.doi.org/10.3889/oamjms.2019.841 Text en Copyright: © 2019 Nguyen Truong Giang, Trung Nguyen Ngoc, Nguyen Van Nam, Nguyen Viet Nhung, Ta Ba Thang, Dong Khac Hung, Nguyen Duy Bac, Chu Dinh Toi, Pham Ngoc Hung. http://creativecommons.org/licenses/CC BY-NC/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0) |
spellingShingle | Basic and Clinical Medical Researches in Vietnam Giang, Nguyen Truong Ngoc, Trung Nguyen Nam, Nguyen Van Nhung, Nguyen Viet Thang, Ta Ba Hung, Dong Khac Bac, Nguyen Duy Toi, Chu Dinh Hung, Pham Ngoc Lung Volume Reduction Surgery in Patients with Heterogenous Emphysema: Selecting Perspective |
title | Lung Volume Reduction Surgery in Patients with Heterogenous Emphysema: Selecting Perspective |
title_full | Lung Volume Reduction Surgery in Patients with Heterogenous Emphysema: Selecting Perspective |
title_fullStr | Lung Volume Reduction Surgery in Patients with Heterogenous Emphysema: Selecting Perspective |
title_full_unstemmed | Lung Volume Reduction Surgery in Patients with Heterogenous Emphysema: Selecting Perspective |
title_short | Lung Volume Reduction Surgery in Patients with Heterogenous Emphysema: Selecting Perspective |
title_sort | lung volume reduction surgery in patients with heterogenous emphysema: selecting perspective |
topic | Basic and Clinical Medical Researches in Vietnam |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084044/ https://www.ncbi.nlm.nih.gov/pubmed/32215100 http://dx.doi.org/10.3889/oamjms.2019.841 |
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