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Imaging diagnosis for intervertebral disc

Various functional magnetic resonance imaging (MRI) techniques have been investigated in recent years and are being used in clinical practice for the patients with low back pain (LBP). MRI is an important modality for diagnosing intervertebral disc (IVD) degeneration. In recent years, there have bee...

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Autores principales: Ogon, Izaya, Takebayashi, Tsuneo, Takashima, Hiroyuki, Morita, Tomonori, Terashima, Yoshinori, Yoshimoto, Mitsunori, Yamashita, Toshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084050/
https://www.ncbi.nlm.nih.gov/pubmed/32211585
http://dx.doi.org/10.1002/jsp2.1066
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author Ogon, Izaya
Takebayashi, Tsuneo
Takashima, Hiroyuki
Morita, Tomonori
Terashima, Yoshinori
Yoshimoto, Mitsunori
Yamashita, Toshihiko
author_facet Ogon, Izaya
Takebayashi, Tsuneo
Takashima, Hiroyuki
Morita, Tomonori
Terashima, Yoshinori
Yoshimoto, Mitsunori
Yamashita, Toshihiko
author_sort Ogon, Izaya
collection PubMed
description Various functional magnetic resonance imaging (MRI) techniques have been investigated in recent years and are being used in clinical practice for the patients with low back pain (LBP). MRI is an important modality for diagnosing intervertebral disc (IVD) degeneration. In recent years, there have been several reported attempts to use MRI T2 mapping and MRI T1ρ mapping to quantify lumbar disc degeneration. MRI T2 mapping involves digitizing water content, proteoglycan content, and collagen sequence breakdown as relaxation times (T2 values) at each site. These digitized values are used to create a map, that is, then used to quantitatively evaluate the metabolite concentrations within IVD tissues. MRI T2 mapping utilizes the T2 relaxation time to quantify moisture content and the collagen sequence breakdown. MRI T1ρ mapping digitizes water molecule dispersion within the cartilaginous matrix to evaluate the degree of cartilaginous degeneration. Magnetic resonance spectroscopy is a less‐invasive diagnostic test that provides biochemical information. Adequate analysis of the IVD has not yet been performed, although there are indications of a relationship between the adipose content of the multifidus muscle in the low back and LBP. The ultra short TE technique has been recently used to investigate lumbar cartilaginous endplates. Unlike diagnosis based on contrast‐enhanced images of the IVD, which depends on the recurrence of pain that is determined subjectively, MRI‐based diagnosis is less‐invasive and based on objective imaging findings. It is therefore expected to play a key role in the diagnostic imaging of IVD conditions in the future.
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spelling pubmed-70840502020-03-24 Imaging diagnosis for intervertebral disc Ogon, Izaya Takebayashi, Tsuneo Takashima, Hiroyuki Morita, Tomonori Terashima, Yoshinori Yoshimoto, Mitsunori Yamashita, Toshihiko JOR Spine Global Review Series: Japan 2020 Various functional magnetic resonance imaging (MRI) techniques have been investigated in recent years and are being used in clinical practice for the patients with low back pain (LBP). MRI is an important modality for diagnosing intervertebral disc (IVD) degeneration. In recent years, there have been several reported attempts to use MRI T2 mapping and MRI T1ρ mapping to quantify lumbar disc degeneration. MRI T2 mapping involves digitizing water content, proteoglycan content, and collagen sequence breakdown as relaxation times (T2 values) at each site. These digitized values are used to create a map, that is, then used to quantitatively evaluate the metabolite concentrations within IVD tissues. MRI T2 mapping utilizes the T2 relaxation time to quantify moisture content and the collagen sequence breakdown. MRI T1ρ mapping digitizes water molecule dispersion within the cartilaginous matrix to evaluate the degree of cartilaginous degeneration. Magnetic resonance spectroscopy is a less‐invasive diagnostic test that provides biochemical information. Adequate analysis of the IVD has not yet been performed, although there are indications of a relationship between the adipose content of the multifidus muscle in the low back and LBP. The ultra short TE technique has been recently used to investigate lumbar cartilaginous endplates. Unlike diagnosis based on contrast‐enhanced images of the IVD, which depends on the recurrence of pain that is determined subjectively, MRI‐based diagnosis is less‐invasive and based on objective imaging findings. It is therefore expected to play a key role in the diagnostic imaging of IVD conditions in the future. John Wiley & Sons, Inc. 2019-09-29 /pmc/articles/PMC7084050/ /pubmed/32211585 http://dx.doi.org/10.1002/jsp2.1066 Text en © 2019 The Authors. JOR Spine published by Wiley Periodicals, Inc. on behalf of Orthopaedic Research Society This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Global Review Series: Japan 2020
Ogon, Izaya
Takebayashi, Tsuneo
Takashima, Hiroyuki
Morita, Tomonori
Terashima, Yoshinori
Yoshimoto, Mitsunori
Yamashita, Toshihiko
Imaging diagnosis for intervertebral disc
title Imaging diagnosis for intervertebral disc
title_full Imaging diagnosis for intervertebral disc
title_fullStr Imaging diagnosis for intervertebral disc
title_full_unstemmed Imaging diagnosis for intervertebral disc
title_short Imaging diagnosis for intervertebral disc
title_sort imaging diagnosis for intervertebral disc
topic Global Review Series: Japan 2020
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084050/
https://www.ncbi.nlm.nih.gov/pubmed/32211585
http://dx.doi.org/10.1002/jsp2.1066
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