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In vitro selection of ribozyme ligases that use prebiotically plausible 2-aminoimidazole–activated substrates
The hypothesized central role of RNA in the origin of life suggests that RNA propagation predated the advent of complex protein enzymes. A critical step of RNA replication is the template-directed synthesis of a complementary strand. Two experimental approaches have been extensively explored in the...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084097/ https://www.ncbi.nlm.nih.gov/pubmed/32123094 http://dx.doi.org/10.1073/pnas.1914367117 |