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Frameshifting preserves key physicochemical properties of proteins

Frameshifts in protein coding sequences are widely perceived as resulting in either nonfunctional or even deleterious protein products. Indeed, frameshifts typically lead to markedly altered protein sequences and premature stop codons. By analyzing complete proteomes from all three domains of life,...

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Detalles Bibliográficos
Autores principales: Bartonek, Lukas, Braun, Daniel, Zagrovic, Bojan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084103/
https://www.ncbi.nlm.nih.gov/pubmed/32127487
http://dx.doi.org/10.1073/pnas.1911203117