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Extracellular Vesicle-Induced Classical Complement Activation Leads to Retinal Endothelial Cell Damage via MAC Deposition
Several studies have suggested that there is a link between membrane attack complex (MAC) deposition in the retina and the progression of diabetic retinopathy (DR). Our recent investigation demonstrated that circulating IgG-laden extracellular vesicles contribute to an increase in retinal vascular p...
Autores principales: | Huang, Chao, Fisher, Kiera P., Hammer, Sandra S., Busik, Julia V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084203/ https://www.ncbi.nlm.nih.gov/pubmed/32121610 http://dx.doi.org/10.3390/ijms21051693 |
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